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(hydroxyamino)benzene mutase

From Wikipedia, the free encyclopedia
(hydroxyamino)benzene mutase
Identifiers
EC no.5.4.4.1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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In enzymology, a (hydroxyamino)benzene mutase (EC 5.4.4.1) is an enzyme that catalyzes the chemical reaction

(hydroxyamino)benzene 2-aminophenol

Hence, this enzyme has one substrate, (hydroxyamino)benzene, and one product, 2-aminophenol.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring hydroxy groups. The systematic name of this enzyme class is (hydroxyamino)benzene hydroxymutase. Other names in common use include HAB mutase, hydroxylaminobenzene hydroxymutase, and hydroxylaminobenzene mutase. This enzyme participates in naphthalene and anthracene degradation.

References

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  • He Z, Nadeau LJ, Spain JC (2000). "Characterization of hydroxylaminobenzene mutase from pNBZ139 cloned from Pseudomonas pseudoalcaligenes JS45. A highly associated SDS-stable enzyme catalyzing an intramolecular transfer of hydroxy groups". Eur. J. Biochem. 267 (4): 1110–6. doi:10.1046/j.1432-1327.2000.01107.x. PMID 10672020.
  • Davis JK, Paoli GC, He Z, Nadeau LJ, Somerville CC, Spain JC (2000). "Sequence analysis and initial characterization of two isozymes of hydroxylaminobenzene mutase from Pseudomonas pseudoalcaligenes JS45". Appl. Environ. Microbiol. 66 (7): 2965–71. doi:10.1128/AEM.66.7.2965-2971.2000. PMC 92098. PMID 10877793.